The experimental Alzheimer's disease drug bapineuzumab appears to be effective in some patients, according to mid-stage study results released Tuesday by drug makers Wyeth and Elan Corp, the Wall Street Journal reported.
In patients with a gene known to increase the risks of Alzheimer's -- and of developing the disease at an earlier stage -- the drug showed statistically significant clinical improvements. This did not occur in patients without the gene, who were at greater risk for fluid buildup in the brain, especially when taking the drug at higher doses.
Detailed results of the study are expected to be presented July 29 at the International Conference on Alzheimer's Disease in Chicago. The drug has received a fast-track designation from the U.S. Food and Drug Administration. It's expected that it will be at least two years before Wyeth and Elan apply for FDA approval of bapineuzumab, the Wall Street Journal reported.
The drug is designed to attack beta-amyloid. Many experts believe that a build-up of this substance in the brain causes Alzheimer's disease.
Wednesday, June 18, 2008
New Alzheimer's Drug Shows Promise
Labels: medications drugs
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